There are more than 80 types of autoimmune diseases identified to date. Many of them share similar symptoms, so that pinpointing the exact autoimmune condition can be a monumentally time-consuming, exasperating task. Many patients are not diagnosed until these initially innocuous symptoms manifest into clinical complaints and sub-optimal health. The detection of autoantibodies can be employed for more specific determination of autoimmune diseases. Autoantibodies can also determine the progress of the disease and whether or not therapy has been effective.
Gastrointestinal Autoimmunity & Gluten Sensitivity
Autoimmune gastritis is characterized by mucosal atrophy and parietal cell loss. Therefore, parietal cell autoantibodies present in the sera of most patients with this disease are a useful diagnostic marker. The autoantibodies correlate with the presence of atrophic gastritis and with disease severity. These antibodies are also detected in patients with celiac disease, autoimmune thyroid disease, type-1 diabetes and other autoimmune endocrinopathies.
Diagnosis of Lyme disease can be difficult because its symptoms share commonalities with ALF, Alzheiner's, autism, chronic fatigue syndrome, fibromyalgia, lupus, Parkinson's and RA. It is crucial to combine clinical symptomatology with the most sensitive techniques available to properly diagnose Lyme disease.
Viruses, in particular, HHV-6, are some of the major contributing factors in autoimmunity. Viruses can also affect the ability of T-cells to detect antigens by cross-reaction (molecular mimicry). If viral infections remain untreated, they may result in over-activation of the immune system, which may subsequently progress to autoimmune diseases. The addition of HHV-6 IgG and IgM to EBV, CMV, HSV, VZV and Measles makes ISL’s viral assessments unique.